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Research about Caloric Restriction, mitochondria and/or Aging

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・Individual evaluation of aging- and caloric restriction-related changes to distinct multimeric complexes of circulating adiponectin by

　immunoblotting

　Kobayashi, M., Nezu, Y., Itoh, M., Uchida, R., Arikawa, T., Otsubo, M., Nozaki, Y., Tagawa, R., Fujishima, Y., Maeda, N., Shimomura,

   I. & Higami, Y.

​　Exp Gerontol. 2022 Jul 164, 111821. doi: 10.1016/j.exger.2022.111821 (IF: 4.03 in 2021/22)

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・Prolonged caloric restriction ameliorates age-related atrophy in slow and fast muscle fibers of rat soleus muscle.

　Mizunoe Y, Kobayashi M, Saito H, Goto A, Migitaka R, Miura K, Okita N, Sudo Y, Tagawa R, Yoshida M, Umemori A, Nakagawa Y, Shimano H, 　Higami Y.

　Exp Gerontol. 2021 Aug 17;154:111519. doi: 10.1016/j.exger.2021.111519. Online ahead of print. (IF: 3.376 in 2019/20）

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・Contribution of PGC-1α to Obesity- and Caloric Restriction-Related Physiological Changes in White Adipose Tissue.

　Kobayashi M, Deguchi Y, Nozaki Y, Higami Y.

　Int J Mol Sci. 2021 Jun 2;22(11):6025. doi: 10.3390/ijms22116025.（IF: 4.602 in 2020）

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・Mitochondrial Unfolded Protein Responses in White Adipose Tissue: Lipoatrophy, Whole-Body Metabolism and Lifespan.

　Kobayashi M, Nezu Y, Tagawa R, Higami Y.

　Int J Mol Sci. 2021 Mar 11;22(6):2854. doi: 10.3390/ijms22062854.（IF: 4.602 in 2020）

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Research about Obesity and/or Autophagy

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・Long-Term Dietary Taurine Lowers Plasma Levels of Cholesterol and Bile Acids

　Tagawa, R., Kobayashi, M., Sakurai, M., Yoshida, M., Kaneko, H., Mizunoe, Y., Nozaki, Y., Okita, N., Sudo, Y. & Higami, Y.

　Int J Mol Sci. 2022 Feb ,23 (3) 1793.  doi: 10.3390/ijms23031793 (IF: 5.542 (2021/22)

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・Trehalose induces SQSTM1/p62 expression and enhances lysosomal activity and antioxidative capacity in adipocytes.

　Kobayashi M, Yasukawa H, Arikawa T, Deguchi Y, Mizushima N, Sakurai M, Onishi S, Tagawa R, Sudo Y, Okita N, Higashi K, Higami Y.

　FEBS Open Bio. 2021 Jan;11(1):185-194. doi: 10.1002/2211-5463.13055. (IF: 2.231 in 2019/20）